Fomicheva N I, Magaletskiĭ I F, Ogiĭ N V, Sazonova L V
Lik Sprava. 1996 Mar-Apr(3-4):130-4.
Results are submitted on the treatment of 192 miners free from manifest signs of silicosis when they first presented with different forms of pulmonary tuberculosis. Tuberculosis in those individuals engaged in the coal industry was found out to poorly respond to treatment. During the period of 1.5-2 years, cicatrization of the cavities of decay occurred in 42.6 percent of the cases, no bacteria were recoverable in 50.0 percent. The treatment results were dependent upon the utilization of combinations of antituberculous drug preparations, routes of their administration and choice of pathogenetic options. The greatest benefit from treatment occurred with izoniazid, rifampicin, ethambutol and intrabronchial instillations of izoniazid.
报告了192名首次出现不同类型肺结核但无矽肺明显体征的矿工的治疗结果。发现从事煤炭行业的这些人患的结核病对治疗反应不佳。在1.5至2年期间,42.6%的病例空洞出现瘢痕化,50.0%的病例未检出细菌。治疗结果取决于抗结核药物制剂的联合使用、给药途径和致病方案的选择。异烟肼、利福平、乙胺丁醇以及异烟肼支气管内滴注治疗效果最佳。