Ivanitskaia N F, Savchenko M V, Sorokina S F, Li Ia B
Lik Sprava. 1996 Mar-Apr(3-4):31-3.
Imbalance was revealed in the proportions of T-lymphocyte subpopulations in those persons engaged in activity in mining employment who had been exposed to a complex of the radiation accident factors. Maximum reduction in the lymphocyte suppressor activity was recordable in those patients in whom the doses of radioactive irradiation received exceeded 25 s Gy. Depression was found of humoral immunity manifested by a drop in the absolute as well as relative numbers of B-lymphocytes and fall in the blood serum levels of Ig G, A. The results of study of clinical-biochemical and immunologic parameters of blood permit individualized therapies be developed, prophylactic measures to be devised to deal with the relevant pathologic processes and conditions in the cohorts examined.
在那些从事矿业工作且暴露于辐射事故综合因素的人员中，T淋巴细胞亚群比例出现失衡。在那些接受放射性照射剂量超过25 s Gy的患者中，可记录到淋巴细胞抑制活性的最大降低。发现体液免疫受到抑制，表现为B淋巴细胞的绝对数量和相对数量下降以及血清Ig G、A水平降低。对血液临床生化和免疫参数的研究结果有助于制定个体化治疗方案，设计预防措施以应对所检查队列中的相关病理过程和状况。
