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[交替性成瘾:关于3例病例]

[Alternating addictions: apropos of 3 cases].

作者信息

Baylé F J, Chignon J M, Adès J, Lôo H

机构信息

Service Hospitalo-Univesitaire de Santé mentale et de Thérapeutique, Centre hospitalier spécialisé Sainte-Anne, Université Paris V.

出版信息

Encephale. 1996 Jul-Aug;22(4):293-7.

PMID:9035985
Abstract

The concept of addiction is now of interest in psychiatry, but is a great subject of controversies. It is now recognized that as different disorders as alcoholism, drug addiction, bulimia, kleptomania, trichotillomania, pathological gambling are to be considered as addictive states. Other pathological behaviours could be included in the addictive spectrum (i.e. suicidal behaviours, compulsive spending). The comorbidity rates of these disorder are elevated in these populations. For example, high comorbidity rates are found between kleptomania and bulimia or drug addiction and pathological gambling. Polyaddictive states are well established. For some subjects, more than one addiction is present in life-time, but not occurring in the same period. We present three patients in whom different addictive states occurred alternately. All the patients had a history of compulsive spending and kleptomania, two of them had a history of bulimia and sexual compulsion. Some clinical characteristics were common: recurrent mood disorder, depression preceeding the addictive state, no psychoactive substance disorder. In all patients, severity of depressive state decreased when addiction appeared. Depressive symptoms varied inversely to addiction severity. The hypothesis about psychopathological links between kleptomania and bulimia on one hand and mood disorders on the other hand has been known for a long time. Kleptomania as other impulsive disorders is, for some authors, understood in the meaning of a "spectrum affective disorder". For these three patients, an antidepressant effect of the behavioural addictions is suggested. In fact, the addictions appeared alternately. The possibility of common psychopathological and/or biological mechanisms for behavioural addiction is supported by these clinical observations, that could contribute to the addiction concept validity.

摘要

成瘾的概念如今在精神病学领域备受关注,但也是一个充满争议的重大话题。现在人们认识到,诸如酒精成瘾、药物成瘾、贪食症、盗窃癖、拔毛癖、病态赌博等不同的病症都应被视为成瘾状态。其他病态行为也可能被纳入成瘾范畴(如自杀行为、强迫性消费)。这些病症在这些人群中的共病率较高。例如,盗窃癖与贪食症之间,或药物成瘾与病态赌博之间存在较高的共病率。多种成瘾状态已得到充分证实。对于一些人来说,一生中会出现不止一种成瘾情况,但并非同时发生。我们介绍三位患者,他们交替出现了不同的成瘾状态。所有患者都有强迫性消费和盗窃癖病史,其中两人有贪食症和性强迫病史。一些临床特征是共同的:反复出现情绪障碍,成瘾状态之前有抑郁发作,无精神活性物质障碍。在所有患者中,成瘾出现时抑郁状态的严重程度降低。抑郁症状与成瘾严重程度呈反比。盗窃癖与贪食症之间以及情绪障碍之间存在精神病理联系的假设由来已久。对于一些作者来说,盗窃癖与其他冲动性病症一样,被理解为“谱系情感障碍”的一种。对于这三位患者,行为成瘾具有抗抑郁作用的观点被提了出来。事实上,成瘾是交替出现的。这些临床观察结果支持了行为成瘾存在共同精神病理和/或生物学机制的可能性,这可能有助于成瘾概念的有效性。

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