[Time organization of blood coagulation in patients with rheumatic heart disease involving circulation insufficiency].

Daily profiles of blood coagulation were studied in 20 normal subjects and 92 patients with rheumatic heart disease with stages I-III circulatory insufficiency before and after traditional therapy and chronotherapy with heparin and curantyl added to traditional therapy with antirheumatic agents, diuretics, and cardiac glycosides. Time organization of the hemostasis was disordered in patients with decompensated heart disease, but it is possible to correct it by chronotherapy with heparin and curantyl.