[Fat-soluble vitamins E and A in the tumor tissue and in the blood of patients with renal-cell cancer].

The level of vitamin E was measured in 31 renal carcinomas and unaffected renal cortex taken as control. Two groups were formed in respect to cell composition of the carcinoma: 14 tumors composed of clear cells; 17 tumors composed of other types cells. Vitamin E concentrations and total lipids in the tumor tissue were elevated. Despite a significant positive correlation between levels of vitamin E and lipids in cancer tissue, high content of lipids is not the main reason of vitamin E accumulation. Concentration of vitamin A measured in 17 carcinomas was similar to control as per 1 mg of tissue lipids. Blood levels of vitamin E and total lipids in 12 patients with renal cell carcinoma were significantly higher than in healthy subjects and returned to normal after nephrectomy.