Verma R S, Kleyman S M
Ann Genet. 1996;39(4):243-5.
We report a new pericentric inversion of chromosome 4 in a female who has had two consecutive fetal losses during the first trimester conception. Cytogenetic findings with GTG-banding revealed a 46,XX,inv(4) (p13q13) karyotype in her peripheral blood cells. The breakpoint on the long arm is different from any other previously described case. A comprehensive bibliography of reported cases with pericentric inversion is also tabulated.
我们报告了一名女性患者，其4号染色体发生了一种新的臂间倒位，该女性在孕早期连续两次发生胎儿丢失。采用GTG显带技术的细胞遗传学检查结果显示，其外周血细胞的核型为46,XX,inv(4)(p13q13)。长臂上的断点与之前报道的任何病例均不同。本文还列出了已报道的臂间倒位病例的综合文献目录。
