Raij T, McEvoy L, Mäkelä J P, Hari R
Brain Research Unit, Helsinki University of Technology, Espoo, Finland.
Brain Res. 1997 Jan 16;745(1-2):134-43. doi: 10.1016/s0006-8993(96)01140-7.
Cortical signals associated with infrequent tone omissions were recorded from 9 healthy adults with a whole-head 122 channel neuromagnetometer. The stimulus sequence consisted of monaural (left or right) 50-ms 1-kHz tones repeated every 0.2 or 0.5 s, with 7% of the tones randomly omitted. Tones elicited typical responses in the supratemporal auditory cortices. Omissions evoked strong responses over temporal and frontal areas, independently of the side of stimulation, with peak amplitudes at 145-195 ms. Response amplitudes were 60% weaker when the subject was not attending to the stimuli. Omission responses originated in supratemporal auditory cortices bilaterally, indicating that auditory cortex plays an important role in the brain's modelling of temporal characteristics of the auditory environment. Additional activity was observed in the posterolateral frontal cortex and in the superior temporal sulcus, more often in the right than in the left hemisphere.
使用全头122通道神经磁强计，从9名健康成年人中记录了与罕见音调缺失相关的皮质信号。刺激序列由单耳（左或右）50毫秒1千赫兹的音调组成，每0.2或0.5秒重复一次，其中7%的音调被随机省略。音调在颞上听觉皮层引发典型反应。缺失在颞叶和额叶区域诱发强烈反应，与刺激侧无关，峰值出现在145 - 195毫秒。当受试者不关注刺激时，反应幅度减弱60%。缺失反应双侧起源于颞上听觉皮层，表明听觉皮层在大脑对听觉环境时间特征的建模中起重要作用。在后外侧额叶皮层和颞上沟观察到额外活动，右侧比左侧半球更常见。
