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青少年慢性关节炎(JCA)的骨科治疗

Orthopaedic management of juvenile chronic arthritis (JCA).

作者信息

Pahle J A

出版信息

Z Rheumatol. 1996 Nov-Dec;55(6):376-87.

PMID:9037745
Abstract

Juvenile chronic arthritis is resulting in joint destruction and frequently also in growth disturbances. In less than 50% pain is the cause of functional disability. It is important for rheumasurgeons to differentiate between the three main types of JCA because of the different prognosis. It is also necessary to realize the involvement of all connective tissue and the multiple organ affections in this disease, especially the kidney-function and the hematopoietic system. The natural course of the disease is characterized by fluctuations between remissions and exacerbations, more irregularly than in the adult type of Rh.A. The good results of rheumasurgery are highly dependent on an interdisciplinary combined unit, preferably working "on the same floor" in daily cooperation. Special training in rheumasurgical operative technique is necessary. Prophylactic measures against joint contractures is of great importance and should be common knowledge of all members of the therapeutic team. During a period of 13 years 528 synovectomies were performed. In a controlled study of open knee-synovectomies, recurrence of the inflammation was rarely seen when a radical early synovectomy had been performed. The centralized unit with well experienced staff, who master the problems of anesthesia, medication, intraoperative blood-transfusion and physiotherapy pre- and post-operatively, may obtain good results in the management of this difficult disease.

摘要

青少年慢性关节炎会导致关节破坏,还常常引起生长障碍。不到50%的患者疼痛是功能残疾的原因。由于预后不同,对风湿外科医生来说,区分青少年慢性关节炎的三种主要类型很重要。还必须认识到这种疾病会累及所有结缔组织和多个器官,尤其是肾功能和造血系统。该疾病的自然病程特点是缓解期和加重期交替出现,比成人型类风湿关节炎更不规律。风湿外科手术的良好效果高度依赖于一个跨学科联合团队,最好是每天在同一楼层合作开展工作。有必要进行风湿外科手术技术的专项培训。预防关节挛缩的措施非常重要,应该是治疗团队所有成员的常识。在13年的时间里,共进行了528例滑膜切除术。在一项关于开放性膝关节滑膜切除术的对照研究中,若早期进行彻底的滑膜切除术,炎症复发很少见。配备经验丰富的工作人员,他们能掌握麻醉、用药、术中输血以及术前和术后理疗等问题的集中治疗单元,在管理这种疑难疾病时可能会取得良好效果。

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