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达卡妓女中的乙肝病毒标志物

Hepatitis B virus markers among the prostitutes of Dhaka.

作者信息

Sattar H, Islam M N

机构信息

Deptt. of Microbiology, Institute of Postgraduate Medicine & Research, Dhaka.

出版信息

Bangladesh Med Res Counc Bull. 1996 Apr;22(1):8-11.

PMID:9037839
Abstract

The objective of this study was to estimate the prevalence of hepatitis B virus (HBV) carrier states among prostitutes in Dhaka. Enzyme linked immunosorbent assay (ELISA) was used to detect HBV markers in a group of 164 prostitutes. Serological evidence of current or past HBV infection was present in 129(78.7%) prostitutes. HBsAg was detected in 16(9.7%) of whom 7(43.7%) were positive for e-antigen and e-antibody was present in another 7 (43.7%). Anti-HBs was detected in 94 (57.3%) of the specimens while anti-HBc in 108(73%) of HBsAg negative sera. Prevalence of HBV markers was 87% and 52.6% in VDRL reactive and non reactive sera respectively. The study indicates that the prevalence of HBV infection is high among the prostitutes in Dhaka city. Infection with Treponema pallidum is associated with increased risk of infection with HBV.

摘要

本研究的目的是估计达卡妓女中乙肝病毒(HBV)携带者状态的流行率。采用酶联免疫吸附测定(ELISA)法检测了164名妓女群体中的HBV标志物。129名(78.7%)妓女有当前或既往HBV感染的血清学证据。16名(9.7%)检测到HBsAg,其中7名(43.7%)e抗原呈阳性,另有7名(43.7%)e抗体呈阳性。94份(57.3%)标本检测到抗-HBs,而在HBsAg阴性血清中108份(73%)检测到抗-HBc。VDRL反应性和非反应性血清中HBV标志物的流行率分别为87%和52.6%。该研究表明,达卡市妓女中HBV感染的流行率很高。梅毒螺旋体感染与HBV感染风险增加有关。

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