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[宫颈癌术后放疗的预后因素]

[Prognostic factors of cervical carcinoma treated with postoperative radiotherapy].

作者信息

Shigematsu N, Ito H, Nishiguchi I, Kawada T, Kutsuki S, Nakayama T, Kumagai H, Uematsu M, Kubo A

机构信息

Department of Radiology, Keio University School of Medicine.

出版信息

Nihon Igaku Hoshasen Gakkai Zasshi. 1997 Jan;57(1):28-33.

PMID:9038060
Abstract

We analyzed 119 patients with cervical carcinoma treated by postoperative radiotherapy from 1983 to 1993. Five- and 10-year survival rates of all patients were 77% and 67%, respectively. The 10-year survival rates for stage I (54 patients) and stage II (65 patients) were 76% and 58%, respectively. Ten-year survival rate for patients with both deep stromal invasion and lymph node metastasis was 37% which was much lower than in those without them (more than 90 %), indicating that they seemed to be factors related to poor prognosis. The results of multivariate analysis showed that the number of metastatic lymph nodes was the most important prognostic factor. Leg edema and intestinal and urinary insufficiency as late complications of postoperative radiotherapy occurred at low incidences and were well tolerated.

摘要

我们分析了1983年至1993年间接受术后放疗的119例宫颈癌患者。所有患者的5年和10年生存率分别为77%和67%。Ⅰ期(54例)和Ⅱ期(65例)患者的10年生存率分别为76%和58%。深部间质浸润和淋巴结转移患者的10年生存率为37%,远低于无上述情况的患者(超过90%),表明这些似乎是预后不良的相关因素。多因素分析结果显示,转移淋巴结数量是最重要的预后因素。术后放疗的晚期并发症如腿部水肿、肠道和泌尿系统功能不全发生率较低,且耐受性良好。

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