Kato A, Yamada H, Yamada T, Ishinaga H
Department of Otolaryngology, Yamada Red Cross Hospital, Mie.
Nihon Jibiinkoka Gakkai Kaiho. 1997 Jan;100(1):45-50. doi: 10.3950/jibiinkoka.100.45.
During a 66-month period, 2849 patients with thyroid gland tumor were examined by fine needle aspiration cytology (FNA) under ultrasonographic imaging at Yamada Red Cross Hospital. Of these patients, 333 received surgical therapy and histological examinations were performed. FNA yielded an accuracy of 92.4%, a specificity of 100% and a sensitivity of 88.3%. There were 16 false-negative reports which were mainly considered to be due to calcified lesions, cystic lesion, or follicular carcinoma. Among the 188 negative cases, 24 cases (12.8%) proved to be positive by repeated FNA-Preoperative FNA provides cytological information and may assist in the determination of the operative indication. This approach resulted in an increased rate of surgery of thyroid malignancies among all thyroid gland surgeries. This method need to be improved to reduce false-negative results and the combination of FNA diagnosis and other examination is necessary.
在66个月的时间里，山田红十字医院对2849例甲状腺肿瘤患者进行了超声引导下细针穿刺细胞学检查（FNA）。其中333例患者接受了手术治疗并进行了组织学检查。FNA的准确率为92.4%，特异性为100%，敏感性为88.3%。有16例假阴性报告，主要原因被认为是钙化病变、囊性病变或滤泡癌。在188例阴性病例中，24例（12.8%）经重复FNA后证实为阳性——术前FNA可提供细胞学信息，有助于确定手术指征。这种方法提高了所有甲状腺手术中甲状腺恶性肿瘤的手术率。该方法需要改进以减少假阴性结果，FNA诊断与其他检查相结合是必要的。
