Soontornniyomkij V, Schelper R I
Department of Pathology (Neuropathology), University of Iowa Hospitals and Clinics, Iowa City 52242, USA.
J Clin Pathol. 1996 Sep;49(9):764-5. doi: 10.1136/jcp.49.9.764.
A case of neurocytoma arising in the rostral pontine region of an 18 year old man is reported. The patient developed a right trochlear nerve palsy and was shown to have a well circumscribed, contrast enhancing mass on magnetic resonance imaging. The tumour was characterised histologically by a uniform population of medium sized round nuclei and slightly eosinophilic cytoplasm or occasional perinuclear halos, with delicate branching capillaries, patches of fibrillary matrix, and occasional perivascular pseudorosettes. Immunohistochemical studies demonstrated strong reactivity for synaptophysin in the fibrillary processes and cytoplasm of tumour cells. The present tumour is an exceptional case of neurocytoma arising in the pons.
报告了一例发生于一名18岁男性脑桥前部区域的神经细胞瘤病例。该患者出现右侧滑车神经麻痹，磁共振成像显示有一个边界清晰、强化的肿块。肿瘤的组织学特征为中等大小圆形细胞核均匀分布，细胞质轻度嗜酸性或偶尔有核周晕，伴有纤细分支的毛细血管、纤维状基质斑以及偶尔的血管周围假菊形团。免疫组织化学研究表明，肿瘤细胞的纤维状突起和细胞质中突触素呈强阳性反应。本病例是发生于脑桥的神经细胞瘤的一个特殊病例。
