Stenström C, Ingvarsson L
Department of Oto-Rhino-Laryngology, University of Lund, Malmö University Hospital, Sweden.
Acta Otolaryngol. 1997 Jan;117(1):87-93. doi: 10.3109/00016489709117997.
In a retrospective study of 179 otitis-prone children and 305 controls, various possible predisposing factors for acute otitis media (AOM) were compared. The children were matched for age and sex. There were 61% boys and 39% girls in the otitis-prone group and 58% boys and 42% girls among the controls. Eighty-eight (49%) of the otitis-prone children experienced > or = 11 episodes of AOM and 162 (53%) of the controls had none or at the most one episode of AOM. There were no differences between the groups concerning dwelling districts, the size of family, number of siblings or the education and occupation of the parents. In the otitis-prone group there were more fathers who had been otitis-prone as children. This was not seen for the mothers when comparing all the children, but was seen when comparing the most otitis-prone (> or = 11 AOM) with the controls (0-1 AOM). The otitis-prone children more often had siblings who were otitis-prone compared with the controls. There were no differences between the two groups regarding pregnancy, birthweight or duration of breast-feeding. Thus, male gender and heredity for middle-ear problems appeared to be of importance for otitis-proneness.
在一项针对179名易患中耳炎儿童和305名对照儿童的回顾性研究中，对急性中耳炎（AOM）的各种可能诱发因素进行了比较。这些儿童在年龄和性别上进行了匹配。易患中耳炎组中男孩占61%，女孩占39%；对照组中男孩占58%，女孩占42%。88名（49%）易患中耳炎儿童经历了≥11次AOM发作，162名（53%）对照儿童没有发作或最多发作过1次AOM。两组在居住地区、家庭规模、兄弟姐妹数量或父母的教育程度和职业方面没有差异。在易患中耳炎组中，有更多的父亲在儿童时期易患中耳炎。在比较所有儿童时，母亲的情况并非如此，但在比较最易患中耳炎（≥11次AOM）的儿童与对照儿童（0 - 1次AOM）时可以看到。与对照组相比，易患中耳炎的儿童更常有易患中耳炎的兄弟姐妹。两组在怀孕、出生体重或母乳喂养持续时间方面没有差异。因此，男性性别和中耳问题的遗传因素似乎对易患中耳炎具有重要影响。
