Stephen J, Mara N, Nathwani D
Infection and Immunodeficiency Service, King's Cross Hospital, Dundee Teaching Hospitals NHS Trust.
Br J Clin Pract. 1996 Dec;50(8):468-9.
Around one-third of travellers to endemic areas receive pre-travel typhoid vaccination, increasingly with the new parenteral vaccination Typhim Vi (Mérieux). More than 200 cases of Salmonella typhi and S. paratyphi infection are imported into the UK each year. Despite the widespread use of immunisation, non-specialist clinicians and the travelling public do not appear to fully appreciate the limitations of currently available vaccination. These limitations are not adequately highlighted in either the Green Book of Immunisation against Infectious Diseases (HMSO, 1992) or the new handbook Health Information for Overseas Travel (HMSO, 1995) which are important sources of reference for clinicians and practice nurses. This may delay consideration of diagnosis and presentation for treatment in immunised travellers.
前往伤寒流行地区的旅行者中，约三分之一会在旅行前接种伤寒疫苗，越来越多的人接种新型肠道外疫苗Typhim Vi（赛诺菲巴斯德公司生产）。英国每年有超过200例伤寒沙门氏菌和副伤寒沙门氏菌感染病例输入。尽管疫苗接种广泛使用，但非专科临床医生和旅行公众似乎并未充分认识到现有疫苗接种的局限性。在《传染病免疫绿皮书》（英国皇家文书局，1992年）或新的手册《海外旅行健康信息》（英国皇家文书局，1995年）中，这些局限性都没有得到充分强调，而这两本书是临床医生和执业护士的重要参考资料来源。这可能会延误对接种疫苗旅行者的诊断和治疗。
