Ravetch J V
Laboratory of Molecular Genetics and Immunology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.
Curr Opin Immunol. 1997 Feb;9(1):121-5. doi: 10.1016/s0952-7915(97)80168-9.
In the past year, significant progress in the area of Fc receptor biology has been made in three areas: identification of the protective FcR for serum IgG half-life (Brambell receptor), characterization of the mechanism(s) of inhibitory receptor Fc gamma RIIB signaling, and dissection of the in vivo roles of FcRs in inflammation.
在过去一年里,Fc受体生物学领域在三个方面取得了重大进展:确定了血清IgG半衰期的保护性FcR(布兰贝尔受体),对抑制性受体FcγRIIB信号传导机制进行了表征,以及剖析了FcR在炎症中的体内作用。