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视网膜轴突导向中的埃菲家族

The Eph family in retinal axon guidance.

作者信息

Drescher U, Bonhoeffer F, Müller B K

机构信息

Department of Physical Biology, Max-Planck-Institute for Developmental Biology, Spemannstrasse 35/I, 72076 Tübingen, Germany.

出版信息

Curr Opin Neurobiol. 1997 Feb;7(1):75-80. doi: 10.1016/s0959-4388(97)80123-7.

DOI:10.1016/s0959-4388(97)80123-7
PMID:9039788
Abstract

The continued functional characterization of Eph-related receptors and ligands has provided further information toward an understanding of the mechanisms controlling the retinotectal projection. Recent in vivo analyses have strengthened the idea that Engrailed defines the positional identity of the tectum along the anteroposterior axis, possibly by regulating the expression of Eph family members.

摘要

对Eph相关受体和配体的持续功能特性研究,为理解控制视网膜-脑顶盖投射的机制提供了更多信息。最近的体内分析强化了这样一种观点,即Engrailed可能通过调节Eph家族成员的表达,来确定脑顶盖沿前后轴的位置身份。

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