胰头腺癌根治性切除术：大哈特福德地区的经验
Resection for cure of adenocarcinoma of the head of the pancreas: the greater Hartford experience.
作者信息
Ross H M, Kurtzman S H, Macauly W P, Allen L W, Foster J H, Deckers P J
机构信息
University of Connecticut School of Medicine, USA.
出版信息
Conn Med. 1997 Jan;61(1):3-7.
BACKGROUND
Nationally, the results of pancreaticoduodenectomy for adenocarcinoma of the pancreas have improved. Therefore, we examined our experience with this operation.
METHODS
A retrospective review of tumor registry data from four greater Hartford, Connecticut, hospitals identified 51 patients who underwent pancreaticoduodenectomy for adenocarcinoma of the head of the pancreas between 1982 and 1992.
RESULTS
The 30-day operative mortality rate for the group was 4%. Life table survival analysis revealed a five-year survival rate of 15% and a median survival of 15 months. Twelve patients had postoperative radiation therapy and chemotherapy. The median survival in this group was 36 months, significantly longer than that of the nonadjuvant therapy group (13 months, P < .02). No difference in operative mortality or ultimate survival was seen between the hospital with the largest experience and the three other hospitals.
CONCLUSIONS
Pancreaticoduodenectomy can be performed safely at hospitals with relatively low pancreaticoduodenectomy volume. Survival rates are longer than in past reviews.
背景
在全国范围内，胰腺癌胰十二指肠切除术的结果已有改善。因此，我们审视了我们在该手术方面的经验。
方法
对来自康涅狄格州大哈特福德地区四家医院的肿瘤登记数据进行回顾性分析，确定了1982年至1992年间51例行胰十二指肠切除术治疗胰头腺癌的患者。
结果
该组患者30天手术死亡率为4%。生命表生存分析显示五年生存率为15%，中位生存期为15个月。12例患者接受了术后放疗和化疗。该组患者的中位生存期为36个月，显著长于未接受辅助治疗的组（13个月，P < 0.02）。经验最丰富的医院与其他三家医院在手术死亡率或最终生存率方面未发现差异。
结论
在胰十二指肠切除术例数相对较少的医院也能安全地开展胰十二指肠切除术。生存率高于以往的报道。
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