VanderWall K J, Kohl T, Adzick N S, Silverman N H, Hoffman J I, Harrison M R
Department of Surgery, University of California, San Francisco, USA.
J Pediatr Surg. 1997 Feb;32(2):223-5; discussion 225-6. doi: 10.1016/s0022-3468(97)90183-4.
It is difficult to predict survival of fetuses diagnosed prenatally with congenital diaphragmatic hernia. Some studies suggest that left heart underdevelopment is associated with poor outcome, but fetal echocardiographic variables have not been conclusively proven to be good predictors of postnatal survival. The authors reviewed detailed fetal echocardiographic studies in twelve fetuses with congenital diaphragmatic hernia. Ten echocardiographic variables, including left and right ventricular width, left ventricular volume, and left ventricular mass, were examined from a four-chamber view, corrected for gestational age, and compared with normal data. The results of this study showed no significant differences between survivors and nonsurvivors in the ten variables analyzed. Although left heart dimensions and left ventricular volume in fetuses with congenital diaphragmatic hernia were below the expected normal range, these results did not predict postnatal outcome.
产前诊断为先天性膈疝的胎儿的存活情况很难预测。一些研究表明，左心发育不全与不良预后相关，但胎儿超声心动图变量尚未被确凿证明是出生后存活的良好预测指标。作者回顾了12例先天性膈疝胎儿的详细胎儿超声心动图研究。从四腔心切面检查了10个超声心动图变量，包括左右心室宽度、左心室容积和左心室质量，校正胎龄后与正常数据进行比较。这项研究的结果显示，在分析的10个变量中，存活者和非存活者之间没有显著差异。虽然先天性膈疝胎儿的左心尺寸和左心室容积低于预期正常范围，但这些结果并不能预测出生后的预后。
