Hartfield D S, Lowry N J, Keene D L, Yager J Y
Department of Pediatrics, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Pediatr Neurol. 1997 Jan;16(1):50-3. doi: 10.1016/s0887-8994(96)00290-1.
Iron deficiency is a common pediatric problem affecting 20%-25% of the world's infants. Most commonly causing anemia, iron deficiency is also implicated in such neurologic sequelae as irritability, lethargy, headaches, developmental delay, and infrequently papilledema, pseudotumor cerebri, and cranial nerve abnormalities. Rarely has iron deficiency been recognized as a significant cause of stroke in the adult or pediatric populations. We report a series of 6 children, 6 to 18 months of age, who presented with an ischemic stroke or venous thrombosis after a viral prodrome. All patients had iron deficiency as a consistent finding among the group, and other known etiologies of childhood stroke were excluded. These patients provide evidence of a strong association between iron deficiency and ischemic events in children between 6 and 18 months of age.
缺铁是一种常见的儿科问题，影响着全球20%-25%的婴儿。缺铁最常见的后果是导致贫血，它还与易怒、嗜睡、头痛、发育迟缓等神经后遗症有关，较少见的还有视乳头水肿、假性脑瘤和颅神经异常。缺铁很少被认为是成人或儿科人群中风的重要原因。我们报告了一系列6名6至18个月大的儿童，他们在病毒前驱症状后出现缺血性中风或静脉血栓形成。所有患者均有缺铁这一共同特征，且排除了其他已知的儿童中风病因。这些患者证明了6至18个月大儿童缺铁与缺血性事件之间存在密切关联。
