奥美拉唑诱发的急性间质性肾炎。
Omeprazole-induced acute interstitial nephritis.
作者信息
d'Adamo G, Spinelli C, Forte F, Gangeri F
机构信息
Nephrology and Dialysis Unit, Ospedale Santa Spirito, Rome, Italy.
出版信息
Ren Fail. 1997 Jan;19(1):171-5. doi: 10.3109/08860229709026272.
PMID:9044464
Abstract
Omeprazole is a proton pump inhibitor widely used for the treatment of peptic ulcer disease. We report a patient presenting nonoliguric acute renal failure following omeprazole treatment. Both eosinophilia and eosinophiluria were observed, and the patient was diagnosed as having drug-induced acute interstitial nephritis. Renal failure spontaneously resolved when omeprazole was discontinued.
摘要
奥美拉唑是一种广泛用于治疗消化性溃疡疾病的质子泵抑制剂。我们报告了一例在使用奥美拉唑治疗后出现非少尿型急性肾衰竭的患者。观察到嗜酸性粒细胞增多和嗜酸性粒细胞尿，该患者被诊断为药物性急性间质性肾炎。停用奥美拉唑后，肾衰竭自发缓解。
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