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[喉黏液纤毛清除功能:β2 激动剂、β受体拮抗剂和α激动剂的影响。一项在兔身上的实验研究]

[Laryngeal mucociliary clearance: influence of beta-2 agonists, beta antagonists, and alpha-agonists. An experimental study in rabbits].

作者信息

Armengot M, Garín L, Zapater E, Campos A, Basterra J

机构信息

Servicio de ORL, Hospital General Universitario, Facultad de Medicina, Valencia.

出版信息

Acta Otorrinolaringol Esp. 1996 Nov-Dec;47(6):425-8.

PMID:9044579
Abstract

Laryngeal mucociliary clearance was studied in 35 rabbit larynxes in the immediate post mortem period using charcoal powder. Mucociliary currents flowed from the subglottic walls to the posterior commissure. The normal laryngeal mucociliary clearance rate was 3.7 +/- 1.1 mm/min. Salbutamol accelerated mucociliary clearance (p < 0.01). Propranolol significantly reduced the mucociliary clearance rate (p < 0.001). Mucociliary clearance was not observed in any methoxamine-treated larynxes.

摘要

在35个兔喉的尸检即刻期,使用炭粉对喉黏液纤毛清除功能进行了研究。黏液纤毛流从声门下壁流向后联合。正常喉黏液纤毛清除率为3.7±1.1毫米/分钟。沙丁胺醇加速了黏液纤毛清除(p<0.01)。普萘洛尔显著降低了黏液纤毛清除率(p<0.001)。在任何用甲氧明处理的喉中均未观察到黏液纤毛清除。

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