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[使用准分子激光光治疗性角膜切削术治疗复发性角膜糜烂]

[Treatment of recurrent corneal erosion using phototherapeutic keratectomy with the excimer laser].

作者信息

Lohmann C P, Sachs H, Gabel V P

机构信息

Universitäts-Augenklinik, Regensburg.

出版信息

Klin Monbl Augenheilkd. 1996 Nov;209(5):304-8. doi: 10.1055/s-2008-1035323.

Abstract

BACKGROUND

Recurrent corneal erosion is a common corneal disease and may be a difficult disorder to treat with a number of patients suffering persistent symptoms despite conventional therapy.

PATIENTS AND METHODS

We present a series of 32 eyes who underwent Excimer-Laser phototherapeutic keratectomy (PTK) for recurrent corneal erosion. There were 11 eyes who were treated during an acute episode of recurrent erosion. All remaining patients were treated in a symptom-free interval. The affected area of epithelium was removed and a 25 pulse ablation was performed to Bowman's membrane.

RESULTS

In 30 eyes there was a marked improvement in symptoms postoperatively with no recurrences. However, 2 eyes experienced a recurrent episode 6 days and 2 weeks after PTK, respectively. Postoperative refraction and corneal topography was unaltered in all cases.

CONCLUSIONS

Excimer-Laser PTK appears to be a safe and promising procedure for recurrent corneal erosion in cases refractory to medical treatment.

摘要

背景

复发性角膜糜烂是一种常见的角膜疾病,对于许多患者而言,尽管接受了传统治疗,但仍可能难以治愈,会出现持续症状。

患者与方法

我们报告了一系列32只接受准分子激光角膜切削术(PTK)治疗复发性角膜糜烂的眼睛。其中11只眼睛在复发性糜烂的急性发作期接受治疗。其余所有患者均在无症状期接受治疗。去除上皮的受累区域,并对Bowman膜进行25次脉冲消融。

结果

30只眼睛术后症状明显改善,无复发。然而,2只眼睛分别在PTK术后6天和2周出现复发。所有病例术后屈光和角膜地形图均未改变。

结论

对于药物治疗无效的复发性角膜糜烂病例,准分子激光PTK似乎是一种安全且有前景的治疗方法。

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