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[加泰罗尼亚地区的乳腺癌风险]

[The risk of breast cancer in Catalonia].

作者信息

Izquierdo A, Viladiu P, Borrás J, Galcerán J, Borràs J M, Dorca J, Vayreda J, Moreno V

机构信息

Unidad de Epidemiologia y Registro de Cáncer de Girona, Plaza Hospital.

出版信息

Med Clin (Barc). 1996 Oct 5;107(11):410-3.

PMID:9045002
Abstract

BACKGROUND

To evaluate the risk of developing breast cancer among Catalan women and to estimate the number of new cases of this tumor that appear annually in Catalonia (north-east of Spain).

MATERIAL AND METHODS

The incidence rates of breast cancer were used in the period 1985-1989 proceeding from the population-based cancer registries of Tarragona and Girona. The age-specific rates (ASR) in Catalonia were estimated by an ASR average of Girona and Tarragona, that were adjusted by the standardized mortality ratio (SMR) of these health regions in relation to Catalonia. The cumulative rate and the risk of developing breast cancer were calculated, considering the probability of death by other causes. The temporal trend of breast cancer incidence was analysed by the Poisson's regression model.

RESULTS

The cumulative risk (0-74 years) for breast cancer among Catalan women was 5.17% (1 out of 19 women). The highest risk of developing breast cancer is in the group of age between 60 and 79 years old. Tarragona and Girona had both a moderate increase that was not statistically significant. About 2,550 new cases of breast cancer have been estimated in 1994 and 2,600 in 1996.

CONCLUSION

The risk of developing breast cancer in Catalonia after adjusting for the probability of dying by other causes, is lower than in other countries of Northern Europe and the United States.

摘要

背景

评估加泰罗尼亚女性患乳腺癌的风险,并估计每年在加泰罗尼亚(西班牙东北部)出现的该肿瘤新病例数。

材料与方法

使用1985 - 1989年期间来自塔拉戈纳和赫罗纳基于人群的癌症登记处的乳腺癌发病率。加泰罗尼亚的年龄别发病率(ASR)通过赫罗纳和塔拉戈纳的ASR平均值估计,并根据这些卫生区域相对于加泰罗尼亚的标准化死亡比(SMR)进行调整。计算累积发病率和患乳腺癌的风险,并考虑其他原因导致死亡的概率。通过泊松回归模型分析乳腺癌发病率的时间趋势。

结果

加泰罗尼亚女性乳腺癌的累积风险(0 - 74岁)为5.17%(19名女性中有1名)。患乳腺癌风险最高的是60至79岁年龄组。塔拉戈纳和赫罗纳的发病率均有适度上升,但无统计学意义。估计1994年约有2550例乳腺癌新病例,1996年约有2600例。

结论

在考虑其他原因导致死亡的概率后,加泰罗尼亚患乳腺癌的风险低于北欧其他国家和美国。

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