[机体对细胞内细菌的防御]
[The body's defense against intracellular bacteria].
作者信息
Tärnvik A
机构信息
Institutionen för infektionssjukdomar, Umeå universitet.
出版信息
Nord Med. 1997 Jan;112(1):10-3.
PMID:9045205
Abstract
The separation of the two pathways of differentiation of CD4 T cells is fundamental to an understanding of host defence against intracellular bacteria. Th1 cells, but not Th2 cells, promote effective host response. Elucidation of the mechanisms responsible for the differentiation of Th1 and Th2 cells will facilitate the development of subcellular vaccines against intracellular bacteria.
摘要
CD4 T细胞分化的两条途径的分离对于理解宿主针对细胞内细菌的防御至关重要。Th1细胞而非Th2细胞促进有效的宿主反应。阐明负责Th1和Th2细胞分化的机制将有助于开发针对细胞内细菌的亚细胞疫苗。
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