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儿童肾小球疾病中针对肾小球基底膜的细胞介导免疫和体液免疫(作者译)

[Cell mediated and humoral immunity against glomerular basement membranes in children with glomerular diseases (author's transl)].

作者信息

Lubec G

出版信息

Monatsschr Kinderheilkd (1902). 1977 Sep;125(9):842-4.

PMID:904646
Abstract

43 patients with glomerular disease and 15 healthy children from 2-15 years of age were examined for the presence of cell mediated immunity against enzymatically solubilized glomerular basement membranes. Peripheral lymphocytes of 3 patients with acute hemorrhagic glomerulonephritis, 10 children with chronic glomerulonephritis and 2 children with congenital nephrotic syndrome showed positive reactivity in form of rosette formation. The application of the test for differential diagnosis between different glomerular diseases is discussed.

摘要

对43例肾小球疾病患者和15名2至15岁的健康儿童进行了检测,以确定是否存在针对酶解可溶性肾小球基底膜的细胞介导免疫。3例急性出血性肾小球肾炎患者、10例慢性肾小球肾炎儿童和2例先天性肾病综合征儿童的外周淋巴细胞以玫瑰花结形成的形式表现出阳性反应。讨论了该检测在不同肾小球疾病鉴别诊断中的应用。

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