Roberts R L, Zullo A, Gustafson E A, Carter C S
Department of Zoology, University of Maryland, College Park 20742, USA.
Horm Behav. 1996 Dec;30(4):576-82. doi: 10.1006/hbeh.1996.0060.
This experiment was designed to examine the hypothesis that perinatal manipulation of gonadal or adrenal steroids can alter the subsequent expression of juvenile parental (alloparenting) and affiliative behavior in prairie voles (Microtus ochrogaster). Corticosterone (PRECORT), testosterone (PRE-TP), or oil injections (PRESES) were given on Prenatal Days 12-20 or on Postnatal Days 1-6 (CORT6, TP6, or SES6, respectively). Alloparenting was reduced significantly in females in the CORT6 group and in males in the TP6 group. Sibling affiliative preferences were increased significantly in PRE-TP females and stranger preferences were increased in TP6 and CORT6 females. The results suggest timing is a critical factor determining whether hormones have a facilitative or inhibitory effect on alloparental and affiliative behavior in prairie voles. In this species, corticosterone and testosterone have similar organizational effects on affiliative behavior in females. Alloparental behavior is inhibited by postnatal corticosterone administration in females and by postnatal testosterone administration in males, whereas prenatal steroid administration had no significant effect on alloparenting in either gender.
围产期对性腺或肾上腺类固醇的操控会改变草原田鼠（Microtus ochrogaster）幼年期亲代抚育行为（异亲抚育行为）和亲和行为的后续表达。在产前第12至20天或产后第1至6天分别注射皮质酮（PRECORT）、睾酮（PRE-TP）或油剂（PRESES）（分别为CORT6、TP6或SES6）。CORT6组的雌性和TP6组的雄性异亲抚育行为显著减少。PRE-TP组雌性的同胞亲和偏好显著增加，TP6组和CORT6组雌性对陌生个体的偏好增加。结果表明，时间是决定激素对草原田鼠异亲抚育行为和亲和行为产生促进还是抑制作用的关键因素。在该物种中，皮质酮和睾酮对雌性亲和行为具有相似的组织效应。产后给雌性注射皮质酮以及给雄性注射睾酮会抑制异亲抚育行为，而产前给予类固醇对两性的异亲抚育行为均无显著影响。
