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[鱼类视网膜水平细胞中的膜电位钳制]

[Membrane potential clamping in the horizontal cells of the fish retina].

作者信息

Trifonov Iu A, Golubtsov K V, Byzov A L, Chailakhian L M

出版信息

Neirofiziologiia. 1977;9(4):402-7.

PMID:904738
Abstract

The membrane potential of horizontal cells was clamped using uniform polarization of a layer of these cells by means of current passed via extracellular electrodes. It is shown that the voltage-current relationship of the nonsynaptic membrane of horizontal cells has in some cases sections with a negative slope. With fast shifts in the clamped potential level the changes in the membrane resistance are completed less than for 20 ms. Comparison of responses to light stimulation recorded with potential clamp and without it showed that participation of the nonsynaptic membrane in generation of responses to light stimulation can change significantly the form of the latter.

摘要

通过细胞外电极通入电流,对一层水平细胞进行均匀极化,从而钳制水平细胞的膜电位。结果表明,水平细胞非突触膜的电压-电流关系在某些情况下存在负斜率部分。当钳制电位水平快速变化时,膜电阻的变化在不到20毫秒内完成。对采用电位钳和未采用电位钳记录的光刺激反应进行比较,结果显示非突触膜参与光刺激反应的产生会显著改变后者的形式。

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