Palma P C, Riccetto C L, Herrmann V, Netto N R
Dept. of Urology, Faculdade de Ciências Médicas da Universidade Estadual de Campinas, UNICAMP, San Paulo, Brazil.
J Endourol. 1997 Feb;11(1):67-70. doi: 10.1089/end.1997.11.67.
A total of 30 women with stress incontinence underwent periurethral injection of autologous fat under spinal anesthesia. The fat was harvested from the abdominal wall by liposuction. Preoperative evaluation consisted of history, physical examination, and urodynamic evaluation. For study purposes, some patients also underwent bladder and urethral ultrasonography and magnetic resonance imaging studies. The first 13 patients received a single periurethral lipoinjection, and the following 17 patients received sequential injections when needed at 3-month intervals. Results were assessed by subjective questionnaire performed at 3 and 12 months. All patients had intrinsic sphincteric deficiency. Of the first group, there were only four patients (31%) cured after 1 year of follow-up. On the other hand, in the group that received repeated injections, there were 11 patients (64%) cured with a mean of two injections at 1-year follow-up. Our results show that this procedure warrants continued clinical investigation because it may be useful in selected cases of urinary stress incontinence.
共有30名压力性尿失禁女性在脊髓麻醉下接受了尿道周围自体脂肪注射。脂肪通过抽脂从腹壁获取。术前评估包括病史、体格检查和尿动力学评估。为了研究目的，一些患者还接受了膀胱和尿道超声检查以及磁共振成像研究。前13名患者接受了单次尿道周围脂肪注射，随后的17名患者在需要时每隔3个月接受序贯注射。在3个月和12个月时通过主观问卷评估结果。所有患者均存在内在括约肌缺陷。第一组中，随访1年后仅有4名患者（31%）治愈。另一方面，在接受重复注射的组中，随访1年时有11名患者（64%）治愈，平均注射两次。我们的结果表明，该手术值得继续进行临床研究，因为它可能对某些压力性尿失禁病例有用。
