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实验动物中的人工晶状体

Intraocular lens in laboratory animals.

作者信息

Eifrig D E, Doughman D J

出版信息

Ophthalmic Surg. 1977 Jun;8(3):149-52.

PMID:904867
Abstract

This report summarized the findings in 40 rabbit eyes undergoing extracapsular cataract extraction, 20 of which underwent intraocular lens implantation. The parameters of postoperative evaluation are shown to be limited by the susceptability of the rabbit cornea to corneal edema in the early postoperative phases. The only apparent parameter of statistical importance in this series, however, was the day at which the intraocular lens implanted eye returned to normal compared to the day that the non-implanted eye returned to normal. The fact that there is a 13-day difference in these eyes and the fact that this difference is statistically significant may be important. Pathologic examination of lens implanted eyes has shown that the surgical objectives of intracapsular loop fixation are quite feasible. Microscopic study also showed that there is minimal tissue response to the materials placed in the anterior chamber in this type of surgery.

摘要

本报告总结了40只接受囊外白内障摘除术的兔眼的研究结果,其中20只接受了人工晶状体植入。术后评估参数显示,在术后早期受兔角膜对角膜水肿易感性的限制。然而,在该系列中唯一具有统计学意义的明显参数是植入人工晶状体的眼睛恢复正常的日期与未植入眼睛恢复正常的日期相比。这些眼睛之间存在13天的差异且该差异具有统计学意义这一事实可能很重要。对植入人工晶状体眼睛的病理检查表明,囊内环固定的手术目标是相当可行的。显微镜研究还表明,在这类手术中,对前房内放置的材料组织反应极小。

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