一种编码NADH：泛醌氧化还原酶亚基B13同源物的人类cDNA。
A human cDNA encoding the homologue of NADH: ubiquinone oxidoreductase subunit B13.
作者信息
Pata I, Tensing K, Metspalu A
机构信息
Tartu University, Institute of Molecular and Cell Biology, Estonian Biocentre, Estonia.
出版信息
Biochim Biophys Acta. 1997 Feb 7;1350(2):115-8. doi: 10.1016/s0167-4781(96)00208-4.
A cDNA encoding the human homologue of bovine NADH:ubiquinone oxidoreductase (complex I of mitochondrial respiratory chain) subunit B13 has been isolated. The clone contains an open reading frame of 348 bp, 23 bp of 5'-untranslated sequence (UTR) and a long 3'UTR of 1088 bp. The deduced amino-acid sequence is 87% identical to bovine B13. Human B13 mRNA expression was observed in all tissues examined with highest levels in heart, skeletal muscle and brain. Southern analysis of human genomic DNA revealed the presence of multigene family.
编码牛NADH：泛醌氧化还原酶（线粒体呼吸链复合体I）亚基B13人类同源物的cDNA已被分离出来。该克隆包含一个348 bp的开放阅读框、23 bp的5'-非翻译序列（UTR）和一个1088 bp的长3'UTR。推导的氨基酸序列与牛B13有87%的同一性。在所有检测的组织中均观察到人类B13 mRNA表达，在心脏、骨骼肌和脑中水平最高。对人类基因组DNA的Southern分析揭示了多基因家族的存在。
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