气相色谱法同时测定血清中的格鲁米特、甲乙哌酮和甲喹酮
Simultaneous determination of glutethimide, methyprylon, and methaqualone in serum by gas liquid chromatography.
作者信息
Anweiler J, Bender G, Höbel M
出版信息
Arch Toxicol. 1976 Jun 8;35(3):187-93. doi: 10.1007/BF00293566.
PMID:9049
Abstract
A gas chromatographic method is described that permits the simultaneous determination of glutethimide, methyprylon, and methaqualone in serum samples. The threshold of sensitivity for each of the three hypnotics is 0.2 mg/1.
摘要
本文描述了一种气相色谱法，可同时测定血清样本中的格鲁米特、甲乙哌酮和甲喹酮。这三种催眠药各自的灵敏度阈值为0.2毫克/升。
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Simultaneous determination of glutethimide, methyprylon, and methaqualone in serum by gas liquid chromatography.气相色谱法同时测定血清中的格鲁米特、甲乙哌酮和甲喹酮
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本文引用的文献
1
[The methyprylon metabolite 2,4,6-trioxo-3,3-diethyl-5-methylpiperidine].[甲乙哌啶酮代谢产物2,4,6-三氧代-3,3-二乙基-5-甲基哌啶]
Arzneimittelforschung. 1966 Apr;16(4):548-50.
2
Rapid chromatographic method for the identification and estimation of glutethemide (Doriden) in blood.血液中格鲁米特（导眠能）的快速色谱鉴定与定量方法
J Lab Clin Med. 1966 Aug;68(2):333-9.
3
[Concentrations ofmethylprylon and its metabolites in urine in poisoning cases].[中毒病例中尿液中甲普龙及其代谢物的浓度]
Arzneimittelforschung. 1969 Jan;19(1):123-5.
4
Gas chromatographic determination of methaqualone, 2-methyl-3-o-tolyl-4(3H)-quinazolinone, at therapeutic levels in human plasma.气相色谱法测定人血浆中治疗浓度的安眠酮（2-甲基-3-邻甲苯基-4(3H)-喹唑啉酮）。
J Chromatogr. 1969 Jun 3;42(1):39-44. doi: 10.1016/s0021-9673(01)80585-9.
5
Determination of glutethimide (Doriden) and its metabolites in biologic specimens.生物样本中格鲁米特（多睡丹）及其代谢物的测定。
Clin Chem. 1968 Jul;14(7):595-609.
6
Profile of sedatives and tranquilizers in serum, as measured by gas-liquid chromatography.通过气液色谱法测定血清中镇静剂和安定药的概况。
Clin Chem. 1971 Mar;17(3):222-8.
7
A method for measuring glutethimide (Doriden) in human serum after intake of therapeutic doses.一种测量摄入治疗剂量后人体血清中格鲁米特（多睡丹）的方法。
J Chromatogr. 1972 Oct 5;72(1):21-7. doi: 10.1016/0021-9673(72)80004-9.
8
Plasma levels and absorption of methaqualone after oral administration to man.口服甲喹酮后人体血浆中的药物水平及吸收情况。
Clin Pharmacol Ther. 1972 Sep-Oct;13(5):719-23. doi: 10.1002/cpt1972135part1719.
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J Chem Educ. 1974 Feb;51(2):133-5. doi: 10.1021/ed051p133.
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