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[儿童期引起横贯性损害的脑膜炎症性疾病(慢性脊髓蛛网膜炎和肥厚性硬脊膜炎)。诊断与治疗(作者译)]

[Meningeal inflammatory diseases causing transverse lesions in childhood (arachnoiditis spinalis chronica and pachymeningitis spinalis hypertrophicans). Diagnosis and treatment (author's transl)].

作者信息

Kurz R, Mohssenipour I, Twerdy K

出版信息

Padiatr Padol. 1977;12(4):365-76.

PMID:904944
Abstract

The Arachnoiditis spinalis and the Pachymeningitis spinals are seldom the cause of neurologic deficit. During infancy both illnesses are extremely rare. One illness with a Arachnoiditis spinalis chronica adhaesiva cystica and, for the first time one with a Pachymeningitis spinalis hypertrophicans could be observed. The signs show parallels to spinal tumors, but when inflammation is the origin, the early starting symptoms of tumors appear relatively late. Symptoms of the radix remain dominant. Myelography shows a typical drop shaped block in the case of Arachnoiditis. Diagnosis can be asured only histologically. Surgery may prevent remaining defects of the spine by decompression and may obtain a permanent success by the removal of local processes. When expanded changes occur, an additional chemotherapy with Prednisolon, perhaps in combination with Endoxan may cure the patient, as shown in our two cases.

摘要

脊髓蛛网膜炎和脊髓硬脊膜炎很少是神经功能缺损的原因。在婴儿期,这两种疾病极为罕见。观察到一例慢性粘连性囊肿性脊髓蛛网膜炎,首次观察到一例肥厚性脊髓硬脊膜炎。这些体征与脊髓肿瘤相似,但当炎症是病因时,肿瘤早期出现的症状相对较晚出现。神经根症状仍然占主导。脊髓造影在脊髓蛛网膜炎病例中显示典型的滴状阻塞。诊断只能通过组织学确定。手术可以通过减压预防脊柱的残留缺陷,并通过切除局部病变可能取得永久性成功。当出现扩展性病变时,如我们的两个病例所示,使用泼尼松龙进行额外的化疗,或许联合环磷酰胺可能治愈患者。

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