Okamura M, Itakura A, Kurauchi O, Hayakawa F, Mizutani S, Tomoda Y
Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Japan.
Int J Gynaecol Obstet. 1997 Jan;56(1):13-8. doi: 10.1016/s0020-7292(96)02780-4.
Our purpose was to assess the applicability of fetal heart rate (FHR) monitoring to detect fetuses at risk of developing periventricular leukomalacia (PVL).
FHR tracings obtained for babies delivered under 33 weeks' gestation and with a birth weight under 2000 g were assessed for baseline heart rate, variability, deceleration and "flip flap' (an oscillatory tracing pattern).
PVL developed in 19 of the 103 infants studied. All of these infants were among the fetuses who exhibited average and increased variability. In addition, PVL was detected in 10 (47.6%) of the 21 flip flap positive fetuses, and in 9 (11.0%) of the 82 flip flap negative fetuses. The incidence of PVL was significantly higher in the flip flap positive fetuses (P < 0.005).
The possibility that an unstable intrauterine environment, reflected by a flip flap pattern, is related to the subsequent development of PVL is indicated.
我们的目的是评估胎儿心率（FHR）监测在检测有发生脑室周围白质软化症（PVL）风险胎儿方面的适用性。
对孕周小于33周且出生体重小于2000克的婴儿的FHR描记图进行评估，分析其基线心率、变异性、减速和“翻转波”（一种振荡描记图模式）。
在103例研究婴儿中，19例发生了PVL。所有这些婴儿都在表现出平均和增加变异性的胎儿之中。此外，在21例翻转波阳性胎儿中有10例（47.6%）检测到PVL，在82例翻转波阴性胎儿中有9例（11.0%）检测到PVL。翻转波阳性胎儿中PVL的发生率显著更高（P<0.005）。
表明由翻转波模式反映的不稳定宫内环境与PVL随后发生有关的可能性。
