Eggertsdóttir A V, Stigen O, Lønaas L, Kolbjørnsen O, Moe L
Department of Small Animal Clinical Sciences, Norwegian College of Veterinary Medicine, Norway.
Acta Vet Scand. 1996;37(4):415-26. doi: 10.1186/BF03548081.
The purpose of this randomized clinical study was to compare the effect of 2 surgical methods in the treatment of gastric dilatation-volvulus (GDV) in dogs. One group of dogs (group A) was treated with and one group (group B) without fixation of the stomach. Group A consisted of 21 cases (including 2 dropouts) and group B of 10 cases. The dogs in group A received decompression, anatomical repositioning of the stomach and a circumcostal gastropexy and the dogs in group B (the control group) received the same treatment without gastropexy. Supportive treatment was the same for both groups. The randomization of the dogs in groups A and B was successful with only small differences between the 2 groups in the breed, age, sex and initial decompression methods. At the end of the study (censoring time), the median survival times were significantly different between group A and group B, respectively 549 and 107 days. There were no recurrences in group A while in group B 3 dogs (50%) experienced a recurrence within 6 months. The overall death rates within the first year were 32% in group A and 80% in group B. The death rates caused by GDV and GDV related causes only, after one year of follow-up, were 19% and 71% for groups A and B, respectively. This study shows that treatment that included circumcostal gastropexy significantly reduced the recurrence of GDV and prolonged the postoperative survival time compared with treatment that did not include fixation of the stomach.
这项随机临床研究的目的是比较两种手术方法治疗犬胃扩张-扭转（GDV）的效果。一组犬（A组）采用胃固定术治疗，另一组（B组）不进行胃固定。A组有21例（包括2例退出研究者），B组有10例。A组犬接受减压、胃的解剖复位和肋周胃固定术，B组犬（对照组）接受相同治疗但不进行胃固定术。两组的支持性治疗相同。A组和B组犬的随机分组成功，两组在品种、年龄、性别和初始减压方法上仅有微小差异。在研究结束时（审查时间），A组和B组的中位生存时间有显著差异，分别为549天和107天。A组无复发，而B组有3只犬（50%）在6个月内复发。A组第一年的总死亡率为32%，B组为80%。随访一年后，仅由GDV及其相关原因导致的死亡率，A组和B组分别为19%和71%。这项研究表明，与不包括胃固定的治疗相比，包括肋周胃固定的治疗显著降低了GDV的复发率并延长了术后生存时间。
