Kalits I A, Leĭsner U T
Probl Endokrinol (Mosk). 1977 Mar-Apr;23(2):6-11.
The authors examined selectively 849 women with complicated obstetrical anamnesis in the past and at random 636 women with the aid of the glucose tolerance test (GTT). The incidence of pathological GTT among women with various types of pathology of pregnancy (24%) was greater than in the control group (16.9%). Diabetes mellitus was revealed in 7.8 and 5.1% of cases, respectively. Some types of pathology of pregnancy were of particular significance in the development of the prediabetic state. A high incidence of GTT of diabetic type was noted in women with perinatal death of the fetus (13.1%) and the neonate (11.8%), in women with a large fetus in combination with other types of pathology of pregnancy (12.6%), and also among women who had delivered three and more large fetuses in the past (19.5%). The incidence of diabetic GTT increased in older and obese women; in marked excess of body weight the percentage of GTT of diabetic type was about the same in all the women under study. Among the women with pathology of pregnancy adiposity developed more frequently and in younger persons, and the excess of body weight was much greater in comparison with the control group. The authors consider that GTT should be conducted in all the women with the mentioned pathology of pregnancy in the anamnesis for the purpose of early detection of diabetes mellitus and also for perinatal fetal protection.
作者对849名既往有复杂产科病史的女性进行了选择性检查，并借助葡萄糖耐量试验（GTT）对636名女性进行了随机检查。在患有各种妊娠病理类型的女性中，病理性GTT的发生率（24%）高于对照组（16.9%）。糖尿病的检出率分别为7.8%和5.1%。某些妊娠病理类型在糖尿病前期状态的发展中具有特别重要的意义。在胎儿围产期死亡的女性（13.1%）和新生儿围产期死亡的女性（11.8%）、胎儿巨大合并其他妊娠病理类型的女性（12.6%）以及既往分娩过三个及以上巨大胎儿的女性（19.5%）中，糖尿病型GTT的发生率较高。糖尿病型GTT的发生率在年龄较大和肥胖的女性中增加；在体重明显超重的情况下，所有研究中的女性糖尿病型GTT的百分比大致相同。在患有妊娠病理的女性中，肥胖更常发生且发病年龄更小，与对照组相比体重超重情况更严重。作者认为，对于所有有上述妊娠病理病史的女性，都应进行GTT检查，以便早期发现糖尿病并保护围产期胎儿。
