Slavina E S, Kuratev L V, Kazeev K N, Kertsman V I, Iundunov V M
Probl Endokrinol (Mosk). 1977 Jul-Aug;23(4):35-9.
The results of examination of ECG in 44 patients suffering from Itsenko-Cushing's disease at different stages of surgical treatment are presented. The data obtained were compared with the blood potassium and sodium levels, 17-KS, and 17-OCS levels in the urine, arterial pressure and cholesterol content. Various ECG changes before the operation were revealed in 39 patients. Signs of enlargement of the left ventricle and deformity of the end part of the ventricular complex (negative T wave and or reduction of S-T segment in I, II, avL V5-6 leads) were found in 8 patients, and deformity of the end part of the ventricular complex without any signs of enlargement of the left ventricle--in 18 patients. There proved to be a significant dependence of the changes in the end port of the ventricular complex on increased urinary excretion of 17-OCS, hypokaliemia and hypernatriemia. Negative ECG changes after bilateral total adrenalectomy was significantly connected with postoperative hypocorticism.
本文呈现了44例处于不同手术治疗阶段的库欣病患者的心电图检查结果。将所得数据与血钾、血钠水平、尿17 -酮类固醇（17 - KS）、尿17 -羟皮质类固醇（17 - OCS）水平、动脉血压及胆固醇含量进行了比较。术前39例患者出现了各种心电图变化。8例患者发现左心室增大及心室复合波终末部分畸形（I、II、avL、V5 - 6导联T波倒置和/或ST段压低），18例患者发现心室复合波终末部分畸形但无左心室增大迹象。结果表明，心室复合波终末部分的变化与尿17 - OCS排泄增加、低钾血症和高钠血症显著相关。双侧肾上腺全切术后心电图的阴性变化与术后肾上腺皮质功能减退显著相关。
