Ripert C, Neves I, Appriou M, Tribouley J, Tribouley-Duret J, Haumont G, Guy M, Trouvé B
Université de Bordeaux 2, France.
Bull Soc Pathol Exot. 1996;89(4):252-8.
Schistosomiasis intercalatum in known to exist in Saõ Tomé since 1988, (Corachan et al.). It is transmitted by Bulinus forskalii, (Brown et al., 1989). Stool, blood and urine specimens have been collected from 380 inhabitants of all age groups living in the small town of Guadalupe close to the Agua Traź river and Agua Polino. The prevalence of schistosomiasis by detection of S. intercalatum eggs in a 10 mg stool thick smear (Kato technique) is 25.5%. An excreted Schistosoma polysaccharide antigen, detected by means of a monoclonal antibody (Ripert et al., 1992), is found in 49.1% of the urine samples. Patients voiding S. intercalatum eggs in stools have been treated with praziquantel (40 mg/kg body weight), as recommended by WHO Expert Committee on Schistosomiasis, but it might be wise to also treat persons excreting antigen in urine. The prevalence of intestinal helminthiasis, ascariasis (73.7%), trichuriasis (73.7%) and necatoriasis have been measured.
自1988年以来，已知圣多美存在间插血吸虫病（科拉尚等人）。它由福氏小泡螺传播（布朗等人，1989年）。已从居住在靠近阿瓜特拉兹河和阿瓜波利诺的小镇瓜达卢佩的各年龄组的380名居民中采集了粪便、血液和尿液样本。通过在10毫克粪便厚涂片（加藤技术）中检测间插血吸虫卵，血吸虫病的患病率为25.5%。在49.1%的尿液样本中发现了一种通过单克隆抗体检测的排泄性血吸虫多糖抗原（里佩特等人，1992年）。按照世界卫生组织血吸虫病专家委员会的建议，对粪便中排出间插血吸虫卵的患者用吡喹酮（40毫克/千克体重）进行了治疗，但对尿液中排泄抗原的人也进行治疗可能是明智的。已对肠道蠕虫病、蛔虫病（73.7%）、鞭虫病（73.7%）和钩虫病的患病率进行了测量。
