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[一名患有高位肠梗阻且胆汁呕吐的黄疸婴儿的胆红素脑病]

[Bilirubin encephalopathy in an icteric bile-vomiting infant with high intestinal obstruction].

作者信息

de Weerd W, Wymenga I I, Bergman K A

机构信息

Academisch Ziekenhuis, Beatrix Kinderkliniek, afd. Neonatologie, Groningen.

出版信息

Ned Tijdschr Geneeskd. 1997 Jan 18;141(3):155-7.

PMID:9053764
Abstract

In a 5-day-old full-term, dehydrated boy with bilious vomiting and a cephalhaematoma, bilirubin encephalopathy was diagnosed at a serum bilirubin level of 395 mumol/l. The patient was rehydrated intravenously and treated with phototherapy and an exchange transfusion, after which the serum bilirubin level decreased. The neurological condition normalised during his stay in the hospital. Hyperbilirubinaemia was caused by an increased enterohepatic circulation due to a high intestinal obstruction and resorption of the cephalhaematoma. Toxicity was caused by dehydration and fasting. Even with new bilirubin guidelines it remains important to distinguish a healthy neonate from an ill jaundiced neonate, because at lower serum bilirubin levels symptoms may occur that fit the clinical picture of a bilirubin encephalopathy.

摘要

一名5日龄足月儿、脱水男婴,有胆汁样呕吐及头颅血肿,血清胆红素水平为395μmol/L时被诊断为胆红素脑病。该患者接受了静脉补液,并接受光疗和换血治疗,之后血清胆红素水平下降。其神经状况在住院期间恢复正常。高胆红素血症是由高位肠梗阻导致的肠肝循环增加及头颅血肿的吸收所致。毒性反应是由脱水和禁食引起的。即使有了新的胆红素指南,区分健康新生儿和患病黄疸新生儿仍然很重要,因为在较低的血清胆红素水平时,可能会出现符合胆红素脑病临床表现的症状。

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