急性中间期胆红素脑病的可逆性。
Reversibility of acute intermediate phase bilirubin encephalopathy.
作者信息
Hansen Thor Willy Ruud, Nietsch Lutz, Norman Elisabeth, Bjerre Jesper Vandborg, Hascoet Jean-Michel, Mreihil Khalaf, Ebbesen Finn
机构信息
Neonatal Intensive Care Unit, Division of Paediatrics, Oslo University Hospital, Oslo, Norway.
出版信息
Acta Paediatr. 2009 Oct;98(10):1689-94. doi: 10.1111/j.1651-2227.2009.01409.x. Epub 2009 Jul 6.
AIM
To show the potential for reversing acute intermediate to advanced phase bilirubin encephalopathy.
METHODS
Case studies.
RESULTS
Six extremely jaundiced infants had symptoms of intermediate to advanced phase acute bilirubin encephalopathy. The infants were treated aggressively. Two patients had brain magnetic resonance imaging showing increased signals in the globus pallidus. On follow-up, all infants are neurologically normal.
CONCLUSIONS
Intermediate-to-advanced stage acute bilirubin encephalopathy may occasionally be reversible. These cases provide a strong argument in favour of rapid and aggressive intervention in infants presenting with extreme jaundice and neurological symptoms.
目的
展示逆转急性中度至重度胆红素脑病的可能性。
方法
病例研究。
结果
6例极度黄疸婴儿出现中度至重度急性胆红素脑病症状。对这些婴儿进行了积极治疗。2例患者的脑部磁共振成像显示苍白球信号增强。随访时，所有婴儿神经功能均正常。
结论
中度至重度急性胆红素脑病偶尔可能是可逆的。这些病例有力地支持了对出现极度黄疸和神经症状的婴儿进行快速积极干预。
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