Matapurkar B G, Rehan H M
Department of Surgery, Maulana Azad Medical College & Associated Lok Nayak Hospital, New Delhi, India.
Indian J Exp Biol. 1996 Oct;34(10):954-8.
Regeneration of ureter in vivo is possible from peritoneal stem cells as both are derivative of embryonal germ layer mesoderm. The peritoneal stem cells are engaged in repair of loss due to normal wear and tear by differentiation and proliferation. With pluripotent nature, they have a capacity to undergo metaplastic transformation to various mesodermal tissues. The intrinsic cell factor along with regional tissue organisers coupled with functional need of the region, a desired metaplastic transformation to ureteric wall components is possible.
由于腹膜干细胞和输尿管均起源于胚胎 germ 层中胚层，因此在体内输尿管可由腹膜干细胞再生。腹膜干细胞通过分化和增殖参与因正常磨损导致的损失修复。因其具有多能性，它们有能力向各种中胚层组织进行化生转化。内在细胞因子与区域组织组织者以及该区域的功能需求相结合，有可能实现向输尿管壁成分的理想化生转化。
