Nor 3es J M, Monsegu M H, de Masfrand V, Oberlin F, Denormandie P, Rémy J M
Internal Medicine Department, Raymond Poincaré Hospital, Garches, France.
Eur J Radiol. 1997 Jan;24(1):71-6. doi: 10.1016/s0720-048x(96)01023-6.
Using two new cases and 70 case reports in the literature as a starting point, the authors focus on the Weismann-Netter-Stuhl syndrome. Weismann-Netter and Stuhl reported the first cases of tibioperoneal diaphyseal toxopachyosteosis in 1954. This syndrome is defined as an anomaly of the diaphyseal part of both tibiae and fibulae with posterior cortical thickening and anterior-posterior bowing. This anomaly is usually bilateral and symmetrical and patients are short. The thickening of the fibula is true tibialisation and is the main feature and the only feature confirming diagnosis. Routine laboratory investigations showed no abnormalities. The authors specify the limits encountered in classifying this anomaly and discuss the degree to which this anomaly is an entity unto itself when compared with rickets sequelae.
作者以两例新病例及文献中的70例病例报告为起点，重点研究魏斯曼 - 内特尔 - 施图尔综合征。魏斯曼 - 内特尔和施图尔于1954年报告了首例胫腓骨干骺端中毒性骨肥厚病例。该综合征定义为双侧胫骨和腓骨干骺端异常，伴有后侧皮质增厚和前后弓形弯曲。这种异常通常是双侧对称的，患者身材矮小。腓骨增厚是真正的胫骨化，是主要特征，也是确诊的唯一特征。常规实验室检查未发现异常。作者明确了在对这种异常进行分类时遇到的局限性，并讨论了与佝偻病后遗症相比，这种异常在多大程度上可自成一类。
