Laborit G, Angiboust R, Papin J P
Rev Electroencephalogr Neurophysiol Clin. 1977 Jan-Mar;7(1):70-5. doi: 10.1016/s0370-4475(77)80037-3.
After reviewing various tests of consciousness which can be used during the post-anaesthetic period, the authors chose to analyse the involvement of the visual receptor during different stages between sleep and complete recovery of consciousness, by an electro-oculographic (EOG) method, providing recordings of the displacement of the optical axis. In states of full consciousness the eye explores a static flat surface in saccades separated by pauses. During sleep caused by anaesthesia or by other types of drugs, the integrity of the eye positioning movements by saccades is impaired, and the EOG shows a sinusoidal recording (smooth movements). In one group of patients, regaining of consciousness was monitored throughout and the EOG reording reflected the clinical state of the patient. In a second group, the state of consciousness was monitored 2 hours after the last injection of the anaesthetic drug, so that correlations could be considered with the type of anaesthesia used. Th conclusion concerns the practical interest of the method (short term hospitalisation after general anaesthetic, medico-legal use due to the existence of a recording) and its basic use in the experimental study of new drugs in man.
在回顾了可用于麻醉后阶段的各种意识测试后，作者选择通过眼电图（EOG）方法分析视觉感受器在睡眠至意识完全恢复的不同阶段的参与情况，该方法可记录光轴的位移。在完全清醒状态下，眼睛以扫视的方式探索一个静止的平面，扫视之间有停顿。在麻醉或其他类型药物引起的睡眠期间，通过扫视进行的眼球定位运动的完整性受损，眼电图显示为正弦记录（平滑运动）。在一组患者中，全程监测意识恢复情况，眼电图记录反映了患者的临床状态。在第二组中，在最后一次注射麻醉药物2小时后监测意识状态，以便能够考虑与所用麻醉类型的相关性。结论涉及该方法的实际应用价值（全身麻醉后的短期住院治疗、因存在记录而具有的法医学用途）及其在人体新药实验研究中的基础应用。
