Claassen C A, Gilfillan S, Orsulak P, Carmody T J, Battaglia J, Rush A J
Parkland Memorial Hospital, Dallas, USA.
Psychiatr Serv. 1997 Mar;48(3):353-8. doi: 10.1176/ps.48.3.353.
This study used laboratory tests to identify current drug and alcohol users among psychotic patients seeking treatment in an urban psychiatric emergency room. Rates of clinician-suspected use and self-reported use were compared, as were treatment and disposition of users and nonusers.
Logistic regression modeling was used to identify factors that differentiated current substance users from nonusers in a sample of 112 psychotic patients.
Laboratory analyses revealed that 24 of the 112 psychotic patients (21 percent) had used alcohol or an illegal substance before visiting the emergency room. Younger age, male gender, African-American ethnicity, clinician-suspected substance use, and presentation in the emergency room between 7 p.m. and 7 a.m. were associated with a higher likelihood of positive results on the urine test. Only five of the patients who had positive results (21 percent) self-reported substance use. Clinicians suspected that 59 patients (53 percent) were under the influence; however, only 17 of those suspected (29 percent) had positive laboratory results. Patients with positive laboratory results required more intense care in the psychiatric emergency room and were more often hospitalized.
Some demographic and clinical factors were associated with concurrent substance use among psychotic patients in the emergency room. Clinicians' suspicions of use in this sample of psychotic patients lacked specificity due to the fact that potential use was suspected in a large number of cases for which laboratory results were negative. In contrast, self-reported use was uncommon among patients with positive results. Because neither clinician judgment nor patient self-report meaningfully predicts current substance use, routine urine drug screens may be appropriate.
本研究采用实验室检测来识别在城市精神科急诊室寻求治疗的精神病患者中当前的药物和酒精使用者。比较了临床医生怀疑的使用率和自我报告的使用率,以及使用者和非使用者的治疗与处置情况。
采用逻辑回归模型来确定在112名精神病患者样本中区分当前物质使用者和非使用者的因素。
实验室分析显示,112名精神病患者中有24名(21%)在就诊急诊室之前使用过酒精或非法物质。年龄较小、男性、非裔美国人种族、临床医生怀疑有物质使用以及在晚上7点至早上7点之间到急诊室就诊与尿检呈阳性结果的可能性较高相关。尿检呈阳性结果的患者中只有5名(占21%)自我报告有物质使用情况。临床医生怀疑59名患者(占53%)受到了影响;然而,这些被怀疑的患者中只有17名(占29%)实验室结果呈阳性。实验室结果呈阳性的患者在精神科急诊室需要更强化的护理,且更常被住院治疗。
一些人口统计学和临床因素与急诊室中精神病患者同时使用物质有关。在这个精神病患者样本中,临床医生对使用情况的怀疑缺乏特异性,因为在大量实验室结果为阴性的病例中也怀疑有潜在使用情况。相比之下,结果呈阳性的患者中自我报告使用情况的并不常见。由于临床医生的判断和患者的自我报告都不能有效预测当前的物质使用情况,常规尿液药物筛查可能是合适的。