al-Homrany M
Department of Medicine, King Saud University, College of Medicine, Abha, Saudi Arabia.
Am J Nephrol. 1997;17(1):32-5. doi: 10.1159/000169068.
Tuberculosis associated with dialysis was studied at the Artificial Kidney Unit (AKU) in Abha, Saudi Arabia. There were 13 tuberculosis patients out of 270 patients on maintenance hemodialysis from August 1986 to July 1993, a prevalence of 4.8%. Ten (77%) were female and 3 (23%) were male, mean age of 51.23 +/- 11.62 years. The main site of tuberculosis was pulmonary in 8 (62%) patients, in contrast to other studies. Mean duration on hemodialysis before diagnosis of tuberculosis was 19.23 +/- 14.43 months and mean duration of symptoms prior to diagnosis was 4.54 +/- 3.38 weeks. Anorexia, fever and weight loss were the main presenting symptoms. The tuberculin test was negative in all patients. Choice of treatment using three or four drug regimens for 12 and 6 months, respectively, led to full recovery in all patients with no recurrence. Despite earlier reports of high mortality in such a group of patients, it is suggested that awareness of the increased prevalence of tuberculosis in dialysis patients, together with recognition of its unusual presentation, culminated in early diagnosis and treatment with successful outcomes.
沙特阿拉伯阿卜哈市人工肾科对与透析相关的结核病进行了研究。在1986年8月至1993年7月期间接受维持性血液透析的270例患者中，有13例结核病患者，患病率为4.8%。10例（77%）为女性，3例（23%）为男性，平均年龄为51.23±11.62岁。与其他研究不同的是，8例（62%）患者结核病的主要部位在肺部。结核病诊断前血液透析的平均时长为19.23±14.43个月，诊断前症状的平均持续时间为4.54±3.38周。主要症状为厌食、发热和体重减轻。所有患者结核菌素试验均为阴性。分别采用三联或四联药物方案治疗12个月和6个月，所有患者均完全康复，无复发。尽管早期报道称这类患者死亡率很高，但有人认为，对透析患者结核病患病率增加的认识，以及对其不寻常表现的识别，最终促成了早期诊断和治疗，并取得了成功的结果。
