Lahl R, Nisch G
Schweiz Arch Neurol Neurochir Psychiatr. 1977;120(2):339-53.
Two cases of leptomeningo-cerebro(-spinal) sarcoidosis which were not clinically diagnosed in two women (22 and 33 years old) are described. The two women died because of this disease, 8 months, and 1 1/2 years, resp., after the first manifestation. In the first case there was a largely isolated local affection of the hypothalamus and neurohypophysis. In the second observation, beside an involvement of the bifurcate lymph nodes and of the lungs, it was only the central nervous system that showed massive diffuse changes partially due to a granulomatous angiitis of cerebral and visceral vessels. On the basis of pathohistology, the differential diagnosis to the histiocytosis X for case 1 and to the granulomatous giant cell angiitis for case 2 are discussed.
本文描述了两名女性（分别为22岁和33岁）患软脑膜-脑（脊髓）结节病但生前未被临床诊断的病例。两名女性均因该病死亡，分别在首次出现症状后的8个月和1年半。第一例主要是下丘脑和神经垂体的局限性孤立性病变。在第二例中，除了双侧淋巴结和肺部受累外，仅中枢神经系统出现大量弥漫性改变，部分原因是脑和内脏血管的肉芽肿性血管炎。基于病理组织学，讨论了第一例与组织细胞增多症X以及第二例与肉芽肿性巨细胞血管炎的鉴别诊断。
