Slim K, Pezet D, Chipponi J, Boulant J, Mathieu S
Department of General and Digestive Surgery, Hôtel-Dieu, Clermont-Ferrand, France.
Hepatogastroenterology. 1997 Jan-Feb;44(13):11-5.
BACKGROUND/AIM: The feasibility and safety of the laparoscopic myotomy having been previously demonstrated, the purpose of this prospective study was to evaluate its effectiveness.
Eight patients with primary esophageal achalasia underwent a laparoscopic modified Heller's myotomy with a posterior fundoplication. Early post-operative course has been uneventful in all cases. Clinical, endoscopic, and manometric prospective evaluations were performed with a median follow-up of 21 months (range 4-40).
Excellent or good clinical results were present in all cases. Endoscopic studies were normal in all cases and the post-operative esophageal manometry (n = 7) showed that the median pressure of the lower esophageal sphincter decreased to 8.5 mmHg (range 3-9) which was significant compared to the median pre-operative value of 35 mmHg (p < 0.01).
Though this experience is limited, these mean-term results suggest that the laparoscopic myotomy is effective to treat achalasia. It combines the efficacy of surgery and the minimally invasive aspect of dilatations. Thus, a prospective controlled trial comparing laparoscopic myotomy and dilatations is needed.
背景/目的:腹腔镜肌切开术的可行性和安全性此前已得到证实,本前瞻性研究的目的是评估其有效性。
8例原发性食管贲门失弛缓症患者接受了腹腔镜改良Heller肌切开术并加做后胃底折叠术。所有病例术后早期过程均顺利。进行了临床、内镜和测压前瞻性评估,中位随访时间为21个月(范围4 - 40个月)。
所有病例临床结果均为优或良。所有病例内镜检查均正常,术后食管测压(n = 7)显示食管下括约肌中位压力降至8.5 mmHg(范围3 - 9),与术前中位值35 mmHg相比有显著差异(p < 0.01)。
尽管该经验有限,但这些中期结果表明腹腔镜肌切开术治疗贲门失弛缓症有效。它结合了手术的疗效和扩张术的微创特点。因此,需要进行一项比较腹腔镜肌切开术和扩张术的前瞻性对照试验。