Suppr超能文献

腹腔镜下原发性贲门失弛缓症肌切开术:前瞻性评估

Laparoscopic myotomy for primary esophageal achalasia: prospective evaluation.

作者信息

Slim K, Pezet D, Chipponi J, Boulant J, Mathieu S

机构信息

Department of General and Digestive Surgery, Hôtel-Dieu, Clermont-Ferrand, France.

出版信息

Hepatogastroenterology. 1997 Jan-Feb;44(13):11-5.

PMID:9058111
Abstract

BACKGROUND/AIM: The feasibility and safety of the laparoscopic myotomy having been previously demonstrated, the purpose of this prospective study was to evaluate its effectiveness.

MATERIALS AND METHODS

Eight patients with primary esophageal achalasia underwent a laparoscopic modified Heller's myotomy with a posterior fundoplication. Early post-operative course has been uneventful in all cases. Clinical, endoscopic, and manometric prospective evaluations were performed with a median follow-up of 21 months (range 4-40).

RESULTS

Excellent or good clinical results were present in all cases. Endoscopic studies were normal in all cases and the post-operative esophageal manometry (n = 7) showed that the median pressure of the lower esophageal sphincter decreased to 8.5 mmHg (range 3-9) which was significant compared to the median pre-operative value of 35 mmHg (p < 0.01).

CONCLUSION

Though this experience is limited, these mean-term results suggest that the laparoscopic myotomy is effective to treat achalasia. It combines the efficacy of surgery and the minimally invasive aspect of dilatations. Thus, a prospective controlled trial comparing laparoscopic myotomy and dilatations is needed.

摘要

背景/目的:腹腔镜肌切开术的可行性和安全性此前已得到证实,本前瞻性研究的目的是评估其有效性。

材料与方法

8例原发性食管贲门失弛缓症患者接受了腹腔镜改良Heller肌切开术并加做后胃底折叠术。所有病例术后早期过程均顺利。进行了临床、内镜和测压前瞻性评估,中位随访时间为21个月(范围4 - 40个月)。

结果

所有病例临床结果均为优或良。所有病例内镜检查均正常,术后食管测压(n = 7)显示食管下括约肌中位压力降至8.5 mmHg(范围3 - 9),与术前中位值35 mmHg相比有显著差异(p < 0.01)。

结论

尽管该经验有限,但这些中期结果表明腹腔镜肌切开术治疗贲门失弛缓症有效。它结合了手术的疗效和扩张术的微创特点。因此,需要进行一项比较腹腔镜肌切开术和扩张术的前瞻性对照试验。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验