Suzuki C, Higaki S, Nishiaki M, Mitani N, Yanai H, Tada M, Okita K
First Department of Internal Medicine, Yamaguchi University School of Medicine, Japan.
J Gastroenterol. 1997 Feb;32(1):78-82. doi: 10.1007/BF01213300.
Secondary amyloidosis frequently involves the gastrointestinal tract and may result in ulceration, hemorrhage, and protein-losing enteropathy. We report a patient with severe hypoalbuminemia in whom endoscopy revealed widespread ulceration of the small intestine. The protein-losing site was detected by 99mTc-diethylene triamine pentaacetic acid human serum albumin (99mTc HSA-D) scintigraphy. This evidence suggests that the ulcers and mucosal lesions associated with amyloidosis contribute to abnormal protein loss from the gastrointestinal tract.
继发性淀粉样变性常累及胃肠道，可导致溃疡、出血及蛋白丢失性肠病。我们报告一例严重低白蛋白血症患者，内镜检查发现小肠广泛溃疡。通过99m锝-二乙三胺五乙酸人血清白蛋白（99mTc HSA-D）闪烁扫描检测到蛋白丢失部位。这一证据表明，与淀粉样变性相关的溃疡和黏膜病变导致胃肠道异常蛋白丢失。
