Mathew N T
Houston Headache Clinic, Texas, USA.
Neurol Clin. 1997 Feb;15(1):61-83. doi: 10.1016/s0733-8619(05)70295-4.
This article discusses the use of serotonin1D agonists in the treatment of acute migraine. Specifically, the author reviews the efficacy and safety of this class of drugs with sumatriptan as the main focus. Agents under clinical trial are also discussed. Recurrence of migraine, long-term usage, and side effects of serotonin1D agonists are included in the review. The article also discusses alternative medications, such as intranasal lidocraine, intravenous chlorpromazine, and intravenous prochlorperazine, for acute treatment of migraine. The limited role of narcotics and sedatives is also mentioned.
本文讨论了5-羟色胺1D激动剂在急性偏头痛治疗中的应用。具体而言，作者以舒马曲坦为主要关注点，回顾了这类药物的疗效和安全性。还讨论了处于临床试验阶段的药物。偏头痛的复发、长期使用以及5-羟色胺1D激动剂的副作用也包含在综述中。本文还讨论了用于急性偏头痛治疗的替代药物，如鼻内利多卡因、静脉注射氯丙嗪和静脉注射丙氯拉嗪。文中也提到了麻醉药和镇静剂的有限作用。
