Miller A, Ryan P F, Dowling J P
Department of Medicine, Monash Medical School, Alfred Hospital, Prahran, Victoria, Australia.
J Rheumatol. 1997 Mar;24(3):598-600.
Inflammatory vasculopathy and thrombotic thrombocytopenic purpura (TTP) are rare complications of scleroderma. We report a 54-year-old woman with limited cutaneous scleroderma who developed medium size and small vessel vasculitis. Inflammatory changes of medium size muscular arteries presented as ovarian vasculitis and mononeuritis multiplex, while arteriolar involvement presented as TTP with associated central nervous system involvement. In addition, possible noninflammatory involvement of small muscular arteries was expressed as Raynaud's phenomenon.
炎症性血管病和血栓性血小板减少性紫癜（TTP）是硬皮病的罕见并发症。我们报告一名54岁有限皮肤型硬皮病女性患者，其出现了中小血管血管炎。中等大小肌性动脉的炎症改变表现为卵巢血管炎和多发性单神经炎，而小动脉受累表现为伴有中枢神经系统受累的TTP。此外，小肌性动脉可能的非炎症性受累表现为雷诺现象。
