Monteagudo M, Vidal G, Andreu J, Oristrell J, Tolosa C, Larrosa M, Casanovas A, Almirall J
Department of Internal Medicine, Consorci Hospitalari Parc Tauli, Barcelona, Spain.
J Rheumatol. 1997 Mar;24(3):605-7.
Renal involvement is unusual in giant cell (temporal) arteritis (GCA). Microscopic hematuria and minimal proteinuria responsive to steroid therapy have been described as the most frequent renal alterations. The nephrotic syndrome in GCA has been rarely reported. We describe 2 cases of GCA with nephrotic syndrome, one at the time of diagnosis, the other 2 years after treatment. Percutaneous renal biopsy in both cases disclosed secondary renal amyloidosis confirmed by permanganate sensitivity and immunohistochemical analysis. To our knowledge, cases of GCA and secondary amyloidosis have not been reported.
肾脏受累在巨细胞（颞）动脉炎（GCA）中并不常见。显微镜下血尿和对类固醇治疗有反应的微量蛋白尿被描述为最常见的肾脏改变。GCA合并肾病综合征的报道很少。我们描述了2例GCA合并肾病综合征的病例，1例在诊断时出现，另1例在治疗2年后出现。两例均经皮肾活检，通过高锰酸盐敏感性和免疫组化分析确诊为继发性肾淀粉样变性。据我们所知，尚未有GCA与继发性淀粉样变性病例的报道。
